Publications

25. Iridium Pyridylpyrrolides Hyperpolarised by Para-Hydrogen.
R. M. Majchrzak, P. L. Norcott, Chem. – Eur. J., 2024, https://doi.org/10.1002/chem.202400472.

24. Benzoquinone Enhances Hyperpolarization of Surface Alcohols with Para-Hydrogen.
P. L. Norcott, J. Am. Chem. Soc., 2023, 145, 9970-9975. Cover Article.

23. Anticancer activities of tetra-substituted imidazole-pyrimidine-sulfonamide hybrids as inhibitors of EGFR mutants.
E. M. Alghamdi, Z. M. Alamshany, M. A. El Hamd, E. S. Taher, M. F. El-Behairy, P. L. Norcott, A. A. Marzouk, ChemMedChem, 2023, e202200641.

22. Selective NMR detection of individual reaction components hyperpolarised by reversible exchange with para-hydrogen.
P. L. Norcott, Phys. Chem. Chem. Phys., 2022, 24, 13527-13533.

21. Current Electrochemical Approaches to Selective Deuteration.
P. L. Norcott, Chem. Commun., 2022, 58, 2944-2953.

20. SABRE Hyperpolarised Anti-Cancer Agents for use in ¹H MRI.
E. J. Fear, A. J. Kennerley, P. J. Rayner, P. Norcott, S. S. Roy, S. B. Duckett, Magn. Reson. Med., 2022, 88, 11-27.

19. Simple acyclic molecules containing a single charge-assisted O–H group can recognize anions in acetonitrile: water mixtures.
R. J. Goodwin, M. T. Blyth, A. K. K. Fung, L. M. Smith, P. L. Norcott, S. Tanovic, M. L. Coote, N. G. White, Org. Biomol. Chem., 2021, 19, 2794-2803.

18. Recent Advances in the Chemistry of Benzo[e][1,2,4]triazinyl Radicals.
F. J. M. Rogers, P. L. Norcott, M. L. Coote, Org. Biomol. Chem., 2020, 18, 8255-8277.

17. TEMPO–Me: An Electrochemically Activated Methylating Agent.
P. L. Norcott, C. L. Hammill, B. B. Noble, J. C. Robertson, A. Olding, A. C. Bissember, M. L. Coote, J. Am. Chem. Soc., 2019, 141, 15450-15455. Cover Article.

16. Mechanism of Oxidative Alkoxyamine Cleavage: The Surprising Role of Solvent and Supporting Electrolyte.
B. B. Noble, P. L. Norcott, C. L. Hammill, S. Ciampi, M. L. Coote, J. Phys. Chem. C, 2019, 123, 10300-10305.

15. Effect of Chemical Structure on the Electrochemical Cleavage of Alkoxyamines.
C. L. Hammill, B. B. Noble, P. L. Norcott, S. Ciampi, M. L. Coote, J. Phys. Chem. C, 2019, 123, 5273-5281.

14. Catalyst-Substrate Effects on Biocompatible SABRE Hyperpolarization.
A. Manoharan, P. J. Rayner, M. Fekete, W. Iali, P. Norcott, V. H. Perry, S. B. Duckett, ChemPhysChem, 2019, 20, 285-294.

13. Unlocking a diazirine long-lived nuclear singlet state via photochemistry: NMR detection and lifetime of an unstabilised diazo-compound.
B. Procacci, S. S. Roy, P. Norcott, N. Turner, S. B. Duckett, J. Am. Chem. Soc., 2018, 140, 16855-16864.

12. Fine-tuning the efficiency of para-hydrogen-induced hyperpolarization by rational N-heterocyclic carbene design.
P. J. Rayner, P. Norcott, K. Appleby, W. Iali, R. John, S. Hart, A. Whitwood, S. B. Duckett, Nature Communications, 2018, 9, 4251.

11. Synthesis of Highly Enantio-Enriched Heliespirones A and C by a Diastereoselective Aromatic Claisen Rearrangement.
P. Norcott, C. S. P. McErlean, Aust. J. Chem., 2018, 71, 366-372.

10. Using ²H Labelling to Improve the NMR Detectability of a Series of Pyridines by SABRE.
P. Norcott, M. J. Burns, P. J. Rayner, R. E. Mewis, S. B. Duckett, Mag. Res. Chem., 2018, 56, 663-671.

9. Achieving High ¹H Nuclear Hyperpolarization Levels with Long Lifetimes in a Range of Tuberculosis Drug Scaffolds.
P. Norcott, P. J. Rayner, G. G. R. Green, S. B. Duckett, Chem. – Eur. J., 2017, 23, 16990-16997.

8. A Simple Route to Strong Carbon-13 NMR Signals Detectable for Several Minutes.
S. S. Roy, P. Norcott, P. J. Rayner, G. G. R. Green, S. B. Duckett, Chem. – Eur. J., 2017, 23, 10496-10500. Highlighted in Angew. Chem. Int. Ed. 2017, 56, 10274-10277.

7. Delivering Strong ¹H Nuclear Hyperpolarization Levels and Long Magnetic Lifetimes through Signal Amplification by Reversible Exchange.
P. J. Rayner, M. J. Burns, A. M. Olaru, P. Norcott, M. Fekete, G. G. R. Green, L. A. R. Highton, R. E. Mewis, S. B. Duckett, Proc. Natl. Acad. Sci., 2017, 114, E3188-E3194

6. A Hyperpolarizable ¹H Magnetic Resonance Probe for Signal Detection 15 Minutes after Spin Polarization Storage.
S. S. Roy, P. Norcott, P. J. Rayner, G. G. R. Green, S. B. Duckett, Angew. Chem. Int. Ed., 2016, 55, 15642-15645.

5. Long-lived States to Sustain SABRE Hyperpolarised Magnetisation.
S. S. Roy, P. J. Rayner, P. Norcott, G. G. R. Green, S. B. Duckett, Phys. Chem. Chem. Phys., 2016, 18, 24905-24911.

4. Overview of the synthesis of carbazoloquinone natural products.
A. R. Norman, P. Norcott, C. S. P. McErlean, Tetrahedron Lett., 2016, 57, 4001-4008.

3. Synthesis of carbazoloquinone natural products ‘on-water.’
P. Norcott, C. S. P. McErlean, Org. Biomol. Chem., 2015, 13, 6866-6878.

2. Total Synthesis of (−)-Heliespirone A and (+)-Heliespirone C.
P. Norcott, C. S. P. McErlean, Eur. J. Org. Chem., 2014, 23, 5056-5062.

1. An in-water, on-water domino process for synthesis.
P. Norcott, C. Spielman, C. S. P. McErlean, Green Chem., 2012, 14, 605-609.